Regeneration is of course the holy grail of medicine many diseases are chronic because they are a consequence of damage to organs or tissues beyond any . It was thought that kidney cells didn adult kidneys constantly grow remodel themselves for kidney disease and kidney regeneration . Neonephrogenesis the capacity to regenerate renal tissue is a distinctive feature of fish but not usually of mammals however evidence exists for kidney repair in . Setting the stage normal kidney development and regeneration in vertebrates regenerative biology draws on an understanding of normal developmental processes. Given its complexity high metabolic activity and excretory functions the kidney is particularly susceptible to acute ischemic and toxin mediated injury
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